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Those heterozygous are mostly asymptomatic, have no anemia (except during pregnancy).
Thalassemia minor (also called thalassemia trait) may cause no symptoms, but changes in the blood do occur.
Diagnosis of thalassemia minor is confirmed by MVC ( mean corpuscular volume) is slightly decreased; MCH (mean corpuscular hemoglobin) is decreased.
Beta thalassemia
Alpha thalassemia
Thalassemia minor
Thalassemia major
Thalassemia Symptom
In Thalassemia minor, the hemoglobin genes are inherited during conception, one from the mother (egg) and one from the father (sperm).
People with a Thalassemia trait in one gene are known as carriers or are said to have Thalassemia minor .
Educate patients with thalassemia minor about the genetic (hereditary) nature of their disease, and inform them that their immediate family members (ie, parents, siblings, children) may be affected.
Individuals with thalassemia minor (thalassemia trait) usually have asymptomatic mild anemia. This state does not result in mortality or significant morbidity.
Treatment for Thalassemia Minor
Patients with thalassemia minor usually do not require any specific treatment. Some pregnant patients with the beta thalassemia trait may develop concurrent iron deficiency and severe anemia; they may require transfusional support if not responsive to iron repletion modalities.
Inform patients that their condition is hereditary and that physicians sometimes mistake the disorder for iron deficiency.
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